For headache disorders
Cluster Headache is described as the worst pain known to mankind. It is deemed ‘Suicide Headache’. A cluster headache attack causes excruciating one-sided headpain described as a hot burning poker being stabbed into your eye and is accompanied by symptoms such as a swollen eye, nasal congestion, flushed skin and sweating. Each attack can last from 15 minutes up to 4 hours and some sufferers can experience up to 8 attacks per day
Migraine is the 3rd most prevalent disease worldwide and the most prevalent neurological disease. Migraine is more than just a headache. It is a neurological disorder that causes severe head pain accompanied by nausea, vomiting, vision issues and light and sound sensitivities. Migraine attacks can last from 4 hours to 72 hours and in chronic migraine suffers experience migraine attacks for more than 2 full weeks in each month.
The Cause of headache
Headache pain results from signals interacting among the brain, blood vessels and surrounding nerves. During a headache, an unknown mechanism activates specific nerves that affect muscles and blood vessels. These nerves send pain signals to the brain.
Preventing Headache
At Man & Science we are developing technologies to reduce the severity or frequency of headache by using electrical current or precision delivered pharmaceuticals to influence with the nerve pathways involved in headache.
History shows that no two patients are the same. Where one treatment may benefit one sufferer it may not benefit another; where one patient prefers an implanted device another may not. There is currently no treatment panacea for headache. Therefore Man & Science are focused on developing different options to benefit headache sufferers
Neurostimulation
Delivery of electrical current to the occipital nerves located at the back of the head has been shown to improve the severity and frequency of headache attacks. We are developing a novel, minimally invasive, battery free neurostimulation system to reduce the pain and frequency of severe headache attacks, that can be inserted in as little as 20 minutes.
Targeted Drug Delivery
Using our image guided navigation technology, we deliver small doses of pharmaceutical agents with millimetre precision directly to the nerve bundles involved in severe headache, interrupting the nerve signals to reduce the pain and frequency of attacks. Our innovative technology enables patients to benefit from a precision targeted injection as an outpatient in a short 15-minute procedure.
Man & Science team consists of experienced scientists, engineers, and successful start-up founders and entrepreneurs.
We are actively looking for highly talented and motivated people to join our R&D team. If you are starting your career or have a strong experience in active neurostimulation implants, and you are interested in working in a dynamic and motivated team, we are looking forward to receiving your CV and application at jobs@manandscience.com.
